A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop. Until recently, many fast-changing parts of the human genome remained ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying ...

DNA repair is essential for the maintenance of genomic stability and its failure can lead to human disease. Various DNA repair systems exist, such as base excision repair, nucleotide excision repair, ...

The discovery of ancient HHV-6 genomes provides the first time-stamped genetic proof of long-term virus-human coevolution at the DNA level. It also highlights how ancient DNA can illuminate the deep ...

When the rodent cGAS enzyme was inserted into human and mouse cells in the laboratory, the researchers observed that it significantly enhanced the cells' ability to repair DNA and in turn reduced the ...

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe. Using advanced analysis based ...